FIGO staging and classification for gestational trophoblastic neoplasia (2018)
| Stage | Description |
|---|---|
| I | Gestational trophoblastic tumors strictly confined to the uterine corpus |
| II | Gestational trophoblastic tumors extending to the adnexae or to the vagina, but limited to the genital structures |
| III | Gestational trophoblastic tumors extending to the lungs, with or without genital tract involvement |
| IV | All other metastatic sites |
WHO scoring system based on prognostic factors
| Prognostic Factor | 0 | 1 | 2 | 4 |
|---|---|---|---|---|
| Age | Younger than 40 | 40 or older | - | - |
| Previous pregnancy | Hydatidiform mole | Abortion | Full-term pregnancy | - |
| Months since last pregnancy | < 4 | 4 - 6 | 7 - 12 | > 12 |
| Pretreatment hCG (IU/mL) | <103 | 103-104 | 104-105 | <105 |
| Largest tumor size, including uterus | <3cm | 3-4cm | ≥ 5cm | - |
| Site of spread | Lung | Spleen or kidney | Gastrointestinal tract | Brain, liver |
| Number of tumors that have spread* | 0 | 1 - 4 | 5 - 8 | > 8 |
| Number of drugs used to treat the tumor that have not worked | None | None | 1 drug | >2 drugs |